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KMID : 0828620120160020121
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Journal of Korean Arthroscopy Society
2012 Volume.16 No. 2 p.121 ~ p.127
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The Effect of Thromboprophylaxis in Lower Extremity Arthroscopic Surgery on Coagulation Test : Enoxaparin versus Rivaroxaban
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Park Sang-Eun
Back Young-Woong
Kim Jong-Dai
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Abstract
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Purpose: To compare coagulation test results of the arthroscopic surgery patients who received thromboprophylaxis with typical two kinds of anticoagulation drugs, we performed coagulation tests before and after surgery with two groups and then compared the results.
Materials and Methods: Forty-seven patients who underwent arthroscopic surgery were randomly divided into two groups to rivaroxaban and enoxaparin group, and we performed coagulation tests before and 5 days after arthroscopic surgery to two drugs groups in order to investigate about the difference in clotting capacity.
Results: Preoperative coagulation tests did not differ significantly between the two groups. However, coagulation tests after 5 days of the surgery, the level of prothrombin time-international normalized ratio (PT-INR), activated partial thromboplastin time (aPTT) increased, particularly in patients with rivaroxaban compared with enoxaparin (P<0.05).
Conclusion: Anticoagulation for arthroscopic surgery with a drug is effective and has safe range in terms of bleeding tendency, but in the rivaroxaban group, there was one patient who showed high bleeding tendency with abnormal range. Therefore it should be careful of using rivaroxaban for thromboprophylaxis.
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KEYWORD
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Arthroscopy, Thromboprophylaxis, Coagulation test, Enoxaparin, Rivaroxaban
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